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The purpose of the examine would be to characterize the metabolites here of EAM-2201 in human hepatocytes attained in vitro and those in liver and urine specimens received in vivo with the autopsy of an EAM-2201 abuser.
Our in vitro benefits counsel that EAM-2201 must be examined concerning likely in vivo pharmacokinetic drug–drug interactions because of time-dependent inhibition of CYP2C8, CYP2C9, CYP2C19 and CYP3A4 routines and competitive inhibition of UGT1A3 exercise.
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